Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085

Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085

Abstract Background A large number of Fusobacterium nucleatum (Fn) are present in colorectal cancer (CRC) tissues of patients who relapse after chemotherapy, and Fn has been reported to promote oxaliplatin and 5-FU chemoresistance in CRC. Pathogens such as bacteria and parasites stimulate exosome pr...

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Bibliographic Details
Main Authors: Bingqing Hui, Chenchen Zhou, Yetao Xu, Rui Wang, Yuwen Dong, Yirui Zhou, Jie Ding, Xiao Zhang, Jian Xu, Yanhong Gu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Nanobiotechnology
Subjects:
Fusobacterium nucleatum
Exosomes
hsa_circ_0004085
Chemoresistance of colon cancer
Endoplasmic reticulum stress
Online Access:https://doi.org/10.1186/s12951-024-02331-9

Internet

https://doi.org/10.1186/s12951-024-02331-9

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