The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression

<p>Abstract</p> <p>Background</p> <p>RhoH is a constitutively active member of the family of Rho GTPases. Its expression is restricted to the haematopoietic lineage, where it serves as a positive regulator for T cell selection and mast cell function and as a negative re...

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Bibliographic Details
Main Authors: Gündogdu Mehtap S, Liu He, Metzdorf Daniela, Hildebrand Dagmar, Aigner Michael, Aktories Klaus, Heeg Klaus, Kubatzky Katharina F
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/225