Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia

Patients over the age of 70 show inflammaging and a weaker anti-viral response to SARS-CoV-2, pointing at the immunological changes associated with COVID-19 severity and outcome for aged patients.

Bibliographic Details
Main Authors: Domenico Lo Tartaro, Anita Neroni, Annamaria Paolini, Rebecca Borella, Marco Mattioli, Lucia Fidanza, Andrew Quong, Carlene Petes, Geneve Awong, Samuel Douglas, Dongxia Lin, Jordan Nieto, Licia Gozzi, Erica Franceschini, Stefano Busani, Milena Nasi, Anna Vittoria Mattioli, Tommaso Trenti, Marianna Meschiari, Giovanni Guaraldi, Massimo Girardis, Cristina Mussini, Lara Gibellini, Andrea Cossarizza, Sara De Biasi
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03537-z