Drug–Drug Interactions Involving Dexamethasone in Clinical Practice: Myth or Reality?

Drug–Drug Interactions Involving Dexamethasone in Clinical Practice: Myth or Reality?

Concomitant administration of multiple drugs frequently causes severe pharmacokinetic or pharmacodynamic drug–drug interactions (DDIs) resulting in the possibility of enhanced toxicity and/or treatment failure. The activity of cytochrome P450 (CYP) 3A4 and P-glycoprotein (P-gp), a drug efflux pump s...

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Bibliographic Details
Main Authors: Venceslas Bourdin, William Bigot, Anthony Vanjak, Ruxandra Burlacu, Amanda Lopes, Karine Champion, Audrey Depond, Blanca Amador-Borrero, Damien Sene, Chloe Comarmond, Stéphane Mouly
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Journal of Clinical Medicine
Subjects:
dexamethasone
drug–drug interaction
cytochrome P450 (CYP) 3A4
P-glycoprotein(P-gp)
pharmacokinetics
side effect
Online Access:https://www.mdpi.com/2077-0383/12/22/7120

Internet

https://www.mdpi.com/2077-0383/12/22/7120

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