Zinc oxide nanoparticles exacerbate skin epithelial cell damage by upregulating pro-inflammatory cytokines and exosome secretion in M1 macrophages following UVB irradiation-induced skin injury

Zinc oxide nanoparticles exacerbate skin epithelial cell damage by upregulating pro-inflammatory cytokines and exosome secretion in M1 macrophages following UVB irradiation-induced skin injury

Abstract Background Zinc oxide nanoparticles (ZnONPs) are common materials used in skin-related cosmetics and sunscreen products due to their whitening and strong UV light absorption properties. Although the protective effects of ZnONPs against UV light in intact skin have been well demonstrated, th...

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Bibliographic Details
Main Authors: Bour-Jr Wang, Yu-Ying Chen, Hui-Hsuan Chang, Rong-Jane Chen, Ying-Jan Wang, Yu-Hsuan Lee
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Particle and Fibre Toxicology
Subjects:
Zinc oxide nanoparticle
Transepidermal water loss
Lysosomal impairment
Autophagy dysfunction
Macrophage polarization
Exosome
Online Access:https://doi.org/10.1186/s12989-024-00571-z

Internet

https://doi.org/10.1186/s12989-024-00571-z

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