Variable absorption of mutational trends by prion-forming domains during Saccharomycetes evolution
Prions are self-propagating alternative states of protein domains. They are linked to both diseases and functional protein roles in eukaryotes. Prion-forming domains in Saccharomyces cerevisiae are typically domains with high intrinsic protein disorder (i.e., that remain unfolded in the cell during...
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Format: | Article |
Language: | English |
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PeerJ Inc.
2020-08-01
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Series: | PeerJ |
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Online Access: | https://peerj.com/articles/9669.pdf |