Transcriptomic profiling of the developing brain revealed cell-type and brain-region specificity in a mouse model of prenatal stress

Transcriptomic profiling of the developing brain revealed cell-type and brain-region specificity in a mouse model of prenatal stress

Abstract Background Prenatal stress (PS) is considered as a risk factor for many mental disorders. PS-induced transcriptomic alterations may contribute to the functional dysregulation during brain development. Here, we used RNA-seq to explore changes of gene expression in the mouse fetal brain after...

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Bibliographic Details
Main Authors: Yuhao Dong, Jie Weng, Yueyan Zhu, Daijing Sun, Wei He, Qi Chen, Jin Cheng, Ying Zhu, Yan Jiang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Genomics
Subjects:
Maternal stress
Embryonic brain
Gene transcription
Cell-type-specificity
Brain-region-specificity
Online Access:https://doi.org/10.1186/s12864-023-09186-8

Internet

https://doi.org/10.1186/s12864-023-09186-8

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