Elucidating tumor heterogeneity from spatially resolved transcriptomics data by multi-view graph collaborative learning

Multi-view graph approaches could enhance the analysis of tissue heterogeneity in spatial transcriptomics. Here, the authors develop the Spatial Transcriptomics data analysis by Multiple View Collaborative-learning - stMVC - framework, and apply it to detect spatial domains and cell states in brain...

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Bibliographic Details
Main Authors: Chunman Zuo, Yijian Zhang, Chen Cao, Jinwang Feng, Mingqi Jiao, Luonan Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33619-9