Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to engage antiviral functions. Unlike the receptor...

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Bibliographic Details
Main Authors: Yue Yin, Jinglin Ma, Cliff Van Waesberghe, Bert Devriendt, Herman W. Favoreel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
epithelial cell
pseudorabies virus
alphaherpesvirus
type I interferon
type III interferon
respiratory
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1016982/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1016982/full

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