Checkpoint Immunotherapy in Pediatric Oncology: Will We Say Checkmate Soon?

Immune checkpoint inhibitors (ICIs) are a relatively new class of immunotherapy which bolsters the host immune system by “turning off the brakes” of effector cells (e.g., CTLA-4, PD-1, PD-L1). Although their success in treating adult malignancy is well documented, their utility in pediatric cancer h...

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Bibliographic Details
Main Authors: Alexander Ciurej, Elizabeth Lewis, Avanti Gupte, Eman Al-Antary
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/11/12/1843