Chemotherapy and Immune Checkpoint Inhibitors in a Case of SMARCA4-dUT: A Case Report and Review of Literature

SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are infrequently occurring aggressive neoplasms found predominantly in young male smokers. These tumors are distinguished by the loss of expression of Brahma-related gene 1 (BRG1) due to a deactivating mutation of SMARCA4. Immunophenotype can b...

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Bibliographic Details
Main Authors: Akriti Pokhrel MD, Ruchi Yadav MD, Kapil Kumar Manvar MD, Richard Wu MD, Vijay Jaswani MD, Carrie Brooke Wasserman MD, Jen C. Wang MD
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/23247096231176220