Protocol for treating lumbar spinal canal stenosis with a combination of ultrapurified, allogenic bone marrow-derived mesenchymal stem cells and in situ-forming gel: a multicentre, prospective, double-blind randomised controlled trial

Introduction In patients with combined lumbar spinal canal stenosis (LSCS), a herniated intervertebral disc (IVD) that compresses the dura mater and nerve roots is surgically treated with discectomy after laminoplasty. However, defects in the IVD after discectomy may lead to inadequate tissue healin...

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Main Authors: Yoichi M Ito, Toshiyuki Isoe, Norihiro Sato, Hideki Sudo, Norimasa Iwasaki, Khin Khin Tha, Takashi Miyakoshi, Yudai Watanabe, Kaoru Kahata, Nozomi Yokota, Hiroe Kato, Tomoko Terada, Teruyo Arato
Format: Article
Language:English
Published: BMJ Publishing Group 2023-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/2/e065476.full