Design, Synthesis, and Bioactivity Study of Novel Tryptophan Derivatives Containing Azepine and Acylhydrazone Moieties

Design, Synthesis, and Bioactivity Study of Novel Tryptophan Derivatives Containing Azepine and Acylhydrazone Moieties

Based on the scaffolds widely used in drug design, a series of novel tryptophan derivatives containing azepine and acylhydrazone moieties have been designed, synthesized, characterized, and evaluated for their biological activities. The bioassay results showed that the target compounds possessed mod...

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Bibliographic Details
Main Authors: Jingjing Zhang, Rongxin Yang, Lili Li, Jianhua Liu, Yuxiu Liu, Hongjian Song, Qingmin Wang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
tryptophan derivatives
azepino [4,5-<i>b</i>] indole
acylhydrazone
antiviral activity
larvicidal activity
antifungal activity
Online Access:https://www.mdpi.com/1420-3049/27/19/6700

Internet

https://www.mdpi.com/1420-3049/27/19/6700

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