SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway

SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway

High fructose consumption is a significant risking factor for glomerular podocyte injury. However, the causes of high fructose-induced glomerular podocyte injury are still unclear. In this study, we reported a novel mechanism by which high fructose induced ferroptosis, a newly form of programmed cel...

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Bibliographic Details
Main Authors: Wen-Yuan Wu, Zi-Xuan Wang, Tu-Shuai Li, Xiao-Qin Ding, Zhi-Hong Liu, Jie Yang, Lei Fang, Ling-Dong Kong
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Redox Biology
Subjects:
High fructose
Podocyte ferroptosis
SSBP1
DNA-PK
p53
Pterostilbene
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722000751

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http://www.sciencedirect.com/science/article/pii/S2213231722000751

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