Determinants of the level of circulating-tumor HPV16 DNA in patients with HPV-associated oropharyngeal cancer at the time of diagnosis

Determinants of the level of circulating-tumor HPV16 DNA in patients with HPV-associated oropharyngeal cancer at the time of diagnosis

Abstract Circulating tumor HPV DNA (ctHPV16) assessed in liquid biopsy may be used as a marker of cancer in patients with HPV-associated oropharyngeal cancer (HPV + OPC). Factors influencing the initial ctHPV16 quantity are not well recognized. In this study we aimed to establish what factors are re...

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Bibliographic Details
Main Authors: Marek Kentnowski, Alexander J. Cortez, Agnieszka M. Mazurek, Jolanta Mrochem-Kwarciak, Anna Hebda, Urszula Kacorzyk, Katarzyna Drosik-Rutowicz, Ewa Chmielik, Piotr Paul, Karolina Gajda, Izabela Łasińska, Barbara Bobek‑Billewicz, Andrea d’Amico, Krzysztof Składowski, Mirosław Śnietura, Daniel L. Faden, Tomasz W. Rutkowski
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48506-6

Internet

https://doi.org/10.1038/s41598-023-48506-6

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