Comparison of two commercial broad-range PCR and sequencing assays for identification of bacteria in culture-negative clinical samples
Abstract Background Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative samples, amplification and subsequent sequencing of the 16S rRNA gene is oft...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-03-01
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Series: | BMC Infectious Diseases |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12879-017-2333-9 |