ME2 Promotes Proneural–Mesenchymal Transition and Lipogenesis in Glioblastoma

ME2 Promotes Proneural–Mesenchymal Transition and Lipogenesis in Glioblastoma

Malic enzyme 2 (ME2) catalyzes the formation of pyruvate from malic acid and is abnormally expressed in some tumors. However, the exact effects of ME2 on proneural–mesenchymal transition (PMT) and lipogenesis in glioblastoma multiforme (GBM) remain unexplored. Here, we found that ME2 expression was...

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Bibliographic Details
Main Authors: Mengting Yang, Xi Chen, Junyao Zhang, Ermeng Xiong, Qianqian Wang, Wenjing Fang, Li Li, Fei Fei, Aihua Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
malic enzyme 2
glioblastoma
proneural–mesenchymal transition
lipogenesis
AMPK
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.715593/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.715593/full

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