Development of an HPLC-DAD Method for the Extraction and Quantification of 5-Fluorouracil, Uracil, and 5-Fluorodeoxyuridin Monophosphate in Cells and Culture Media of <i>Lactococcus lactis</i>

Development of an HPLC-DAD Method for the Extraction and Quantification of 5-Fluorouracil, Uracil, and 5-Fluorodeoxyuridin Monophosphate in Cells and Culture Media of <i>Lactococcus lactis</i>

The drug 5-fluorouracil (5-FU) is a common cancer chemotherapeutic, presenting toxicity. Mild toxicity is treated with administration of probiotics. The interaction of these probiotics with the drug may have a crucial effect on its therapeutic efficacy. In the present work, a method for the quantifi...

Full description

Bibliographic Details
Main Authors: Petros Mavromatis, Kyriaki Stampouli, Angeliki Vliora, Anna Mayilyan, Victoria Samanidou, Maria Touraki
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Separations
Subjects:
HPLC-DAD
5-Fluorouracil
Uracil
5-fluorodeoxyuridin-monophosphate
probiotics
Online Access:https://www.mdpi.com/2297-8739/9/11/376

Internet

https://www.mdpi.com/2297-8739/9/11/376

Similar Items