Add-on aliskiren treatment can decrease blood pressure but requires attention to risks of renal impairment and hyperkalemia Chikushi Anti-Hypertension Trial-Rasilez® (CHAT-Ras)

Background Renin is the starting point of the renin angiotensin (RA) system cycle. Aliskiren (AL), which is a direct renin inhibitor, suppressed the entire RA cycle. In the present study, the efficacy of add-on of AL treatment in patients with essential hypertension (HT) was investigated. Methods Th...

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Bibliographic Details
Main Authors: Keisuke Okamura, Yosuke Takamiya, Ken Mori, Kazuyuki Shirai, Hidenori Urata
Format: Article
Language:English
Published: Taylor & Francis Group 2020-08-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2020.1723618