FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis

FOXO3a Alleviates the Inflammation and Oxidative Stress via Regulating TGF-β and HO-1 in Ankylosing Spondylitis

This study aimed to investigate whether Forkhead box O3a (FOXO3a) modulates inflammation and oxidative stress in ankylosing spondylitis (AS). We applied bioinformatics analysis, quantitative real-time polymerase chain reaction, immunoblotting, enzyme linked immunosorbent assay, chromatin immunopreci...

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Bibliographic Details
Main Authors: Shanshan Xu, Xiaoyi Zhang, Yubo Ma, Yuting Chen, Huimin Xie, Lingxiang Yu, Jinian Wang, Sheng–qian Xu, Faming Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
ankylosing spondylitis
FOXO3a
TGF-β
HO-1
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.935534/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.935534/full

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