In Vivo Monitoring of the Antiangiogenic Effect of Neurotensin Receptor-Mediated Radiotherapy by Small-Animal Positron Emission Tomography: A Pilot Study

In Vivo Monitoring of the Antiangiogenic Effect of Neurotensin Receptor-Mediated Radiotherapy by Small-Animal Positron Emission Tomography: A Pilot Study

The neurotensin receptor (NTS1) has emerged as an interesting target for molecular imaging and radiotherapy of NTS-positive tumors due to the overexpression in a range of tumors. The aim of this study was to develop a 177Lu-labeled NTS1 radioligand, its application for radiotherapy in a preclinical...

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Bibliographic Details
Main Authors: Simone Maschauer, Tina Ruckdeschel, Philipp Tripal, Roland Haubner, Jürgen Einsiedel, Harald Hübner, Peter Gmeiner, Torsten Kuwert, Olaf Prante
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Pharmaceuticals
Subjects:
neurotensin receptor
positron emission tomography
radiotherapy
lutetium-177
RGD peptide
angiogenesis
Online Access:http://www.mdpi.com/1424-8247/7/4/464

Internet

http://www.mdpi.com/1424-8247/7/4/464

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