The requirement for co-germinants during Clostridium difficile spore germination is influenced by mutations in yabG and cspA.

Clostridium difficile spore germination is critical for the transmission of disease. C. difficile spores germinate in response to cholic acid derivatives, such as taurocholate (TA), and amino acids, such as glycine or alanine. Although the receptor with which bile acids are recognized (germinant rec...

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Bibliographic Details
Main Authors: Ritu Shrestha, Alicia M Cochran, Joseph A Sorg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6464247?pdf=render