Matrix-bound nanovesicle-associated IL-33 supports functional recovery after skeletal muscle injury by initiating a pro-regenerative macrophage phenotypic transition

Abstract Injuries to skeletal muscle are among the most common injuries in civilian and military populations, accounting for nearly 60% of extremity injuries. The standard of care for severe extremity injury has been focused upon limb salvage procedures and the utilization of tissue grafts or orthot...

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Bibliographic Details
Main Authors: J. G. Bartolacci, M. N. Behun, J. P. Warunek, T. Li, A. Sahu, G. K. Dwyer, A. Lucas, J. Rong, F. Ambrosio, H. R. Turnquist, S. F. Badylak
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-024-00346-2