Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection

Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection

Infection with one of the four dengue virus serotypes (DENV1-4) presumably leads to lifelong immunity against the infecting serotype but not against heterotypic reinfection, resulting in a greater risk of developing Dengue Hemorrhagic Fever/Dengue Shock Syndrome (DHF/DSS) during secondary infection....

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Bibliographic Details
Main Authors: Annie Elong Ngono, Hui-Wen Chen, William W Tang, Yunichel Joo, Kevin King, Daniela Weiskopf, John Sidney, Alessandro Sette, Sujan Shresta
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:EBioMedicine
Subjects:
Dengue
Cross-reactivity
T cells
Vaccination
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416304613

Internet

http://www.sciencedirect.com/science/article/pii/S2352396416304613

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