Early Trypanosoma cruzi Infection Triggers mTORC1-Mediated Respiration Increase and Mitochondrial Biogenesis in Human Primary Cardiomyocytes

Early Trypanosoma cruzi Infection Triggers mTORC1-Mediated Respiration Increase and Mitochondrial Biogenesis in Human Primary Cardiomyocytes

Chagasic chronic cardiomyopathy is one of the most frequent and severe manifestations of Chagas disease, caused by the parasite Trypanosoma cruzi. The pathogenic and biochemical mechanisms responsible for cardiac lesions remain not completely understood, although it is clear that hypertrophy and sub...

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Bibliografski detalji
Glavni autori: M. Gabriela Libisch, Paula Faral-Tello, Nisha J. Garg, Rafael Radi, Lucía Piacenza, Carlos Robello
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2018-08-01
Serija:Frontiers in Microbiology
Teme:
Chagas disease
chronic chagasic cardiopathy
host–pathogen
early response to infection
mitochondrial function
Online pristup:https://www.frontiersin.org/article/10.3389/fmicb.2018.01889/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01889/full

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