IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation

IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation

IntroductionThe utilization of denosumab in treating osteoporosis highlights promising prospects for osteoporosis intervention guided by gene targets. While omics-based research into osteoporosis pathogenesis yields a plethora of potential gene targets for clinical transformation, identifying effect...

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Bibliographic Details
Main Authors: Xiangzheng Zhang, Yike Wang, Miao Zheng, Qi Wei, Ruizhi Zhang, Keyu Zhu, Qiaocheng Zhai, Youjia Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteoporosis
IMPC
ROBO1
osteogenesis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1450215/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2024.1450215/full

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