Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator

Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator

Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (INaP) and calcium-activated non-selective cation current (ICAN) are key biophysical factors that, respectively, generate inspiratory rhythm and burst pattern in the mammalian preBö...

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Bibliographic Details
Main Authors: Ryan S Phillips, Hidehiko Koizumi, Yaroslav I Molkov, Jonathan E Rubin, Jeffrey C Smith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
respiratory rhythm generation
pattern generation
computational modeling
preBӧtzinger complex
Online Access:https://elifesciences.org/articles/74762

Internet

https://elifesciences.org/articles/74762

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