Histone demethylase inhibitor GSK-J4 reduces body weight in high-fat diet-induced obese mice

Objective To investigate how histone demethylase inhibitor GSK-J4 could reduce body weight in obese mice fed high-fat diet(HFD). Methods After 16 weeks of feeding C57/BL6 mice with a HFD, GSK-J4 was injected intraperitoneally for 16 days, during which time the body weight and body temperature were m...

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Bibliographic Details
Main Author: CHEN Xin, CHEN Jun, XU Xing, WANG Xu
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2023-09-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-9-1353.pdf