Regulation of otic neurosensory specification by Notch and Wnt signalling: insights from RNA-seq screenings in the embryonic chicken inner ear

Regulation of otic neurosensory specification by Notch and Wnt signalling: insights from RNA-seq screenings in the embryonic chicken inner ear

The Notch and Wnt signalling pathways play key roles in the formation of inner ear sensory organs, but little is known about their transcriptional effectors and targets in this context. Here, we perturbed Notch and Wnt activities in the embryonic chicken otic vesicle using pharmacological treatment...

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Bibliographic Details
Main Authors: Magdalena Żak, Thea P. Støle, Vincent Plagnol, Nicolas Daudet
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Notch signailing pathway
Wnt/β-catenin signaling pathway
RNA-seq-RNA sequencing
prosensory specification
inner ear development
chicken embryo
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1245330/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1245330/full

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