Data‐driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud

Abstract Parameter optimization coupled with model selection is a convenient approach to infer gene regulatory networks from experimental gene expression data, but so far it has been limited to single cells or static tissues where growth is not significant. Here, we present a computational study in...

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Bibliographic Details
Main Authors: Manu Uzkudun, Luciano Marcon, James Sharpe
Format: Article
Language:English
Published: Springer Nature 2015-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20145882