Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy

Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy

Proliferating cancer cells are able to reprogram their energy metabolism, favouring glycolysis even in the presence of oxygen and fully functioning mitochondria. Research is needed to validate the glycolysis-related proteins as prognostic/predictive biomarkers in urothelial bladder carcinoma (UBC),...

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Bibliographic Details
Main Authors: Julieta Afonso, Céline Gonçalves, Marta Costa, Débora Ferreira, Lúcio Santos, Adhemar Longatto-Filho, Fátima Baltazar
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
Warburg effect
glycolysis
hexokinase 2
2-deoxy-D-glucose
urothelial bladder carcinoma
cisplatin resistance
Online Access:https://www.mdpi.com/2072-6694/15/3/982

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https://www.mdpi.com/2072-6694/15/3/982

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