NEUROD2 function is dispensable for human pancreatic β cell specification

NEUROD2 function is dispensable for human pancreatic β cell specification

IntroductionThe molecular programs regulating human pancreatic endocrine cell induction and fate allocation are not well deciphered. Here, we investigated the spatiotemporal expression pattern and the function of the neurogenic differentiation factor 2 (NEUROD2) during human endocrinogenesis.Methods...

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Bibliographic Details
Main Authors: Perla Cota, Lama Saber, Damla Taskin, Changying Jing, Aimée Bastidas-Ponce, Matthew Vanheusden, Alireza Shahryari, Michael Sterr, Ingo Burtscher, Mostafa Bakhti, Heiko Lickert
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
NEUROD2
β cells
endocrinogenesis
iPSC differentiation
endocrine cells
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1286590/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1286590/full

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