Extracellular signal-regulated kinase 5 increases radioresistance of lung cancer cells by enhancing the DNA damage response

Extracellular signal-regulated kinase 5 increases radioresistance of lung cancer cells by enhancing the DNA damage response

Abstract Radiotherapy is a frequent mode of cancer treatment, although the development of radioresistance limits its effectiveness. Extensive investigations indicate the diversity of the mechanisms underlying radioresistance. Here, we aimed to explore the effects of extracellular signal-regulated ki...

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Bibliographic Details
Main Authors: Weiwei Jiang, Guanghui Jin, Fangfang Cai, Xiao Chen, Nini Cao, Xiangyu Zhang, Jia Liu, Fei Chen, Feng Wang, Wei Dong, Hongqin Zhuang, Zi-Chun Hua
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0209-3

Internet

https://doi.org/10.1038/s12276-019-0209-3

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