Lactucin, a Bitter Sesquiterpene from <i>Cichorium intybus</i>, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway

Lactucin, a Bitter Sesquiterpene from <i>Cichorium intybus</i>, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway

Lung cancer, especially adenocarcinoma, is the second most occurring and highest fatality-causing cancer worldwide. Many natural anticancer compounds, such as sesquiterpene lactones (SLs), show promising anticancer properties. Herein, we examined Lactucin, an SL from the plant <i>Cichorium int...

Full description

Bibliographic Details
Main Authors: Khandaker Md Sharif Uddin Imam, Yu Tian, Fengjiao Xin, Yingying Xie, Boting Wen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
lung cancer
adenocarcinoma
NSCLC
apoptosis
cell cycle
ABPP
Online Access:https://www.mdpi.com/1420-3049/27/21/7358

Internet

https://www.mdpi.com/1420-3049/27/21/7358

Similar Items