CellRegMap: a statistical framework for mapping context‐specific regulatory variants using scRNA‐seq
Abstract Single‐cell RNA sequencing (scRNA‐seq) enables characterizing the cellular heterogeneity in human tissues. Recent technological advances have enabled the first population‐scale scRNA‐seq studies in hundreds of individuals, allowing to assay genetic effects with single‐cell resolution. Howev...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2022-08-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.202110663 |