CellRegMap: a statistical framework for mapping context‐specific regulatory variants using scRNA‐seq

CellRegMap: a statistical framework for mapping context‐specific regulatory variants using scRNA‐seq

Abstract Single‐cell RNA sequencing (scRNA‐seq) enables characterizing the cellular heterogeneity in human tissues. Recent technological advances have enabled the first population‐scale scRNA‐seq studies in hundreds of individuals, allowing to assay genetic effects with single‐cell resolution. Howev...

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Bibliographic Details
Main Authors:	Anna S E Cuomo, Tobias Heinen, Danai Vagiaki, Danilo Horta, John C Marioni, Oliver Stegle
Format:	Article
Language:	English
Published:	Springer Nature 2022-08-01
Series:	Molecular Systems Biology
Subjects:	cell‐type specificity eQTL genetic interaction single‐cell sequencing
Online Access:	https://doi.org/10.15252/msb.202110663

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