Transcriptomic characterization of classical monocytes highlights the involvement of immuno-inflammation in bone erosion in Rheumatoid Arthritis

Transcriptomic characterization of classical monocytes highlights the involvement of immuno-inflammation in bone erosion in Rheumatoid Arthritis

IntroductionEvidence-based data suggest that under inflammatory conditions, classical monocytes are the main source of osteoclasts and might be involved in bone erosion pathophysiology. Here, we analyze the transcriptomic profile of classical monocytes in erosive and non-erosive rheumatoid arthritis...

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Bibliographic Details
Main Authors: Lucas Peixoto Sales, Bidossessi Wilfried Hounkpe, Mariana Ortega Perez, Valéria Falco Caparbo, Diogo Souza Domiciano, Eduardo Ferreira Borba, Georg Schett, Camille Pinto Figueiredo, Rosa Maria Rodrigues Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
classical monocytes
bone erosions
inflammation
bone formation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1251034/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1251034/full

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