Differential effects of lysolipids on steroid synthesis in cells expressing endogenous LPA2 receptor1

Differential effects of lysolipids on steroid synthesis in cells expressing endogenous LPA2 receptor1

Incubation of ovarian luteal cells with the bioactive lipid mediator lysophosphatidic acid (LPA) for 180 min abolishes gonadotropin-induced steroid production with no attenuation of the cyclic AMP accumulation. Treatment with the lysolipid also diminishes [14C]steroid production in cells preloaded w...

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Bibliographic Details
Main Authors: Lygia T. Budnik, Bärbel Brunswig-Spickenheier
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Journal of Lipid Research
Subjects:
lysophosphatidic acid
epidermal differentiating gene
sphingosine-1-phosphate
progesterone
steroidogenesis
ovary
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339766

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http://www.sciencedirect.com/science/article/pii/S0022227520339766

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