Elevated LysoGb3 Concentration in the Neuronopathic Forms of Mucopolysaccharidoses

Elevated LysoGb3 Concentration in the Neuronopathic Forms of Mucopolysaccharidoses

Mucopolysaccharidoses (MPSs) are a group of lysosomal storage disorders associated with impaired glycosaminoglycans (GAGs) catabolism. In MPS I, II, III, and VII, heparan sulfate (HS) cannot be degraded because of the lack of sufficient activity of the respective enzymes, and its accumulation in the...

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Bibliographic Details
Main Authors: Galina Baydakova, Alex Ilyushkina, Lidia Gaffke, Karolina Pierzynowska, Igor Bychkov, Agnieszka Ługowska, Grzegorz Wegrzyn, Anna Tylki-Szymanska, Ekaterina Zakharova
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Diagnostics
Subjects:
globotriaosylsphingosine
mucopolysaccharidoses
heparan sulfate
glycosaminoglycans
biochemical marker
inherited metabolic diseases
Online Access:https://www.mdpi.com/2075-4418/10/3/155

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https://www.mdpi.com/2075-4418/10/3/155

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