Linear models enable powerful differential activity analysis in massively parallel reporter assays
Abstract Background Massively parallel reporter assays (MPRAs) have emerged as a popular means for understanding noncoding variation in a variety of conditions. While a large number of experiments have been described in the literature, analysis typically uses ad-hoc methods. There has been little at...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-019-5556-x |