Linear models enable powerful differential activity analysis in massively parallel reporter assays

Abstract Background Massively parallel reporter assays (MPRAs) have emerged as a popular means for understanding noncoding variation in a variety of conditions. While a large number of experiments have been described in the literature, analysis typically uses ad-hoc methods. There has been little at...

Full description

Bibliographic Details
Main Authors: Leslie Myint, Dimitrios G. Avramopoulos, Loyal A. Goff, Kasper D. Hansen
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5556-x