Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy
Selective clearance of damaged mitochondria can reverse pathological status in chronic inflammatory diseases. We recently identified a critical role of nuclear receptor Nur77 and celastrol in priming inflamed mitochondria for autophagy through its mitochondrial targeting and interaction with tumor n...
Автори: | , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Taylor & Francis Group
2018-05-01
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Серія: | Molecular & Cellular Oncology |
Предмети: | |
Онлайн доступ: | http://dx.doi.org/10.1080/23723556.2017.1327005 |