Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy
Selective clearance of damaged mitochondria can reverse pathological status in chronic inflammatory diseases. We recently identified a critical role of nuclear receptor Nur77 and celastrol in priming inflamed mitochondria for autophagy through its mitochondrial targeting and interaction with tumor n...
Asıl Yazarlar: | , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Taylor & Francis Group
2018-05-01
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Seri Bilgileri: | Molecular & Cellular Oncology |
Konular: | |
Online Erişim: | http://dx.doi.org/10.1080/23723556.2017.1327005 |