Effects of the Antitussive Drug Cloperastine on Ventricular Repolarization in Halothane-Anesthetized Guinea Pigs

Cloperastine is an antitussive drug, which can be received as an over-the-counter cold medicine. The chemical structure of cloperastine is quite similar to that of the antihistamine drug diphenhydramine, which is reported to inhibit hERG K+ channels and clinically induce long QT syndrome after overd...

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Bibliografiske detaljer
Main Authors: Akira Takahara, Kaori Fujiwara, Atsushi Ohtsuki, Takayuki Oka, Iyuki Namekata, Hikaru Tanaka
Format: Article
Sprog:English
Udgivet: Elsevier 2012-01-01
Serier:Journal of Pharmacological Sciences
Online adgang:http://www.sciencedirect.com/science/article/pii/S1347861319304311