Impaired bisecting GlcNAc reprogrammed M1 polarization of macrophage

Abstract The functions of macrophages are governed by distinct polarization phenotypes, which can be categorized as either anti-tumor/M1 type or pro-tumor/M2 type. Glycosylation is known to play a crucial role in various cellular processes, but its influence on macrophage polarization is not well-st...

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Bibliographic Details
Main Authors: Xin He, Bowen Wang, Wenli Deng, Jinhua Cao, Zengqi Tan, Xiang Li, Feng Guan
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01432-6