Identification and tracking of HTLV-1–infected T cell clones in virus-associated neurologic disease

Identification and tracking of HTLV-1–infected T cell clones in virus-associated neurologic disease

Human T lymphotropic virus type 1–assoicated (HTLV-1–associated) myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory disease caused by the persistent proliferation of HTLV-1–infected T cells. Here, we performed a T cell receptor (TCR) repertoire analysis focused on HTLV-1–infect...

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Bibliographic Details
Main Authors: Satoshi Nozuma, Eiji Matsuura, Masakazu Tanaka, Daisuke Kodama, Toshio Matsuzaki, Akiko Yoshimura, Yusuke Sakiyama, Shingo Nakahata, Kazuhiro Morishita, Yoshimi Enose-Akahata, Steven Jacoboson, Ryuji Kubota, Hiroshi Takashima
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-04-01
Series:JCI Insight
Subjects:
Inflammation
Virology
Online Access:https://doi.org/10.1172/jci.insight.167422

Internet

https://doi.org/10.1172/jci.insight.167422

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