TWIK-related acid-sensitive K+ channel 2 promotes renal fibrosis by inducing cell-cycle arrest

TWIK-related acid-sensitive K+ channel 2 promotes renal fibrosis by inducing cell-cycle arrest

Summary: TWIK-related acid-sensitive K+ channel-2 (TASK-2, encoded by Kcnk5) is essential in cell biological processes, by regulating transmembrane K+ balance. In the present study, we aimed to clarify the role of TASK-2 in renal fibrosis and explore the underlying mechanism. We found that TASK-2 le...

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Bibliographic Details
Main Authors: Jian Zhang, Jing Chen, Yufei Lu, Yan Yang, Weize Chen, Bo Shen, Jiachang Hu, Ping Jia, Sujuan Xu, Yiqin Shi, Yichun Ning, Jialin Wang, Yi Fang, Shuan Zhao, Yang Li, Yan Dai, Xiaoyan Zhang, Meng Xiang, Yang Tian, Zhichao Liu, Nana Song, Xiaoqiang Ding
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Nephrology
molecular biology
cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222018922

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http://www.sciencedirect.com/science/article/pii/S2589004222018922

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