Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions

Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions

LRRTM1 is a post synaptic adhesion protein, that promotes AMPA receptor mediated synaptic transmission. Here the authors show that LRRTM1 and the adhesion molecule SynCAM 1 act together to organize synapses in the prefrontal cortex with relevance for cognitive function in mice.

Bibliographic Details
Main Authors: Karen Perez de Arce, Adema Ribic, Dhrubajyoti Chowdhury, Katherine Watters, Garth J. Thompson, Basavaraju G. Sanganahalli, Elizabeth T. C. Lippard, Astrid Rohlmann, Stephen M. Strittmatter, Markus Missler, Fahmeed Hyder, Thomas Biederer
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36042-w

Internet

https://doi.org/10.1038/s41467-023-36042-w

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