Removal of lycopene substrate inhibition enables high carotenoid productivity in Yarrowia lipolytica
Substrate inhibition has not been widely studied in the context of synthetic biology and metabolic engineering. Here, the authors report removal of lycopene substrate inhibition by two different strategies and enable high carotenoid productivity in Yarrowia lipolytica.
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-28277-w |