Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments

Purpose: RANKL expression in the tumor microenvironment has been identified as a biomarker of immune suppression, negating the effect of some cancer immunotherapies. Previously we had developed a radiotracer based on the FDA-approved RANKL-specific antibody denosumab, [<sup>89</sup>Zr]Zr...

詳細記述

書誌詳細
主要な著者: Jonatan Dewulf, Ivanna Hrynchak, Sarah Geudens, Isabel Pintelon, Christel Vangestel, José Sereno, Peter A. van Dam, Antero J. Abrunhosa, Filipe Elvas, Tim Van den Wyngaert
フォーマット: 論文
言語:English
出版事項: MDPI AG 2022-04-01
シリーズ:Pharmaceutics
主題:
オンライン・アクセス:https://www.mdpi.com/1999-4923/14/5/939