Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments
Purpose: RANKL expression in the tumor microenvironment has been identified as a biomarker of immune suppression, negating the effect of some cancer immunotherapies. Previously we had developed a radiotracer based on the FDA-approved RANKL-specific antibody denosumab, [<sup>89</sup>Zr]Zr...
Main Authors: | , , , , , , , , , |
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格式: | 文件 |
语言: | English |
出版: |
MDPI AG
2022-04-01
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丛编: | Pharmaceutics |
主题: | |
在线阅读: | https://www.mdpi.com/1999-4923/14/5/939 |