Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease.

Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease.

We previously demonstrated that APP epigenetically regulates Egr1 expression both in cultured neurons and in vivo. Since Egr1 is an immediate early gene involved in memory formation, we wondered whether other early genes involved in memory were regulated by APP and we studied molecular mechanisms in...

Full description

Bibliographic Details
Main Authors: Aurélie Hendrickx, Nathalie Pierrot, Bernadette Tasiaux, Olivier Schakman, Pascal Kienlen-Campard, Charles De Smet, Jean-Noël Octave
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4053420?pdf=render

Internet

http://europepmc.org/articles/PMC4053420?pdf=render

Similar Items